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Side Effects

In Side Effects, every pill is a mystery, and every choice could be your last. Two test subjects. One experiment. Zero guarantees.

The rising dread in Side Effects

Join the horror experiment in Side Effects. Each round, you and your opponent are offered a selection of unknown pills. Some heal. Some hurt. Some do something far stranger. The tension builds with each swallow as effects stack and resistance shifts, until only one of you is left breathing.

How do you play the Side Effects game?

Pill-Driven Tension

Every turn, players must choose:

  • Take a Pill: Accept the consequences of a completely unknown effect.
  • Use an Item: Tools may help, hinder, or mislead. Their use is limited, but powerful.
  • Pass: Sometimes, doing nothing is the most strategic move.

What sets Side Effects apart is its invisible damage system. Your tolerance builds with every pill you take. Reach the limit, and you’re done. But how close are you to breaking? You’ll never really know. That’s the game.

Control Scheme

  • Arrow Keys / WASD: Navigate choices.
  • Enter / Z / Space: Confirm selection.
  • Backspace: Restart match instantly.
  • Mouse (optional): For clicking choices if you’re feeling casual.

Side Effects

Strategic Items and Unreliable Tools

Between rounds, players are offered a rotating collection of items: vaccines, suppressants, even mouth clamps to prevent pill consumption. These aren’t just gimmicks; they’re vital pieces in the chessboard of survival. You’ll need to read your opponent and play smart. Maybe even fake weakness to bait their next move.

AI Opponent with a Pulse

You’re not just swallowing pills in a vacuum. Your opponent reacts. They adapt, observe, and sometimes bluff better than you. The AI (or second player) brings unpredictability to each round, and as resistance tightens, so does the mental grip of the match.

Why Side Effects makes it worth your time?

  • Each match is unique.
  • You never know if you're winning or losing.
  • There are only dangerous moves, no right ones.
  • Both cautious observation and audacious wagers are rewarded in the game.

Because it thrives on ambiguity, Side Effects forces players to embrace discomfort and transforms the simple into a strategy.

Other Spine-Chilling Games Like This

If Side Effects left you with your nerves frayed and your heart pounding, you're not alone. Fans of psychological horror and nerve-wracking gameplay will find a familiar dread in games like Granny Horror, The Man from the Window, and more!

There’s No Cure for What You’ve Swallowed

The pills don’t care what you hope for. They twist. They rot. They linger. You’ve signed the consent form, haven’t you? You said yes without reading. Now, each turn is another incision into your mind. There’s no happy ending here, just a long hallway of blinking lights and the sound of your own breath as it shortens. Keep taking your medicine in Side Effects. It’s already too late to stop.

Horror Games